Abstract

The ultrastructural study of the liver in mice experimentally infected with a local isolate of Trypanosoma evansi reveals changes in the dimensions of the mitochondria and lipid droplets, as well as alterations in some cytoplasmic organelles of the hepatocyte. Likewise, demonstrates modifications in the sinusoid endothelial cell cytoplasm and fenestrae. The quantitative analysis of the qualitative observed changes provides statistical significance to the described changes. The presence of trypomastigotes in sinusoids together with hepatocytes lipid droplets and other observed changes could suggest that the liver is a cryptic target in the life cycle of T. evansi.