Abstract

An ultrastructural study was made in liver biopsies from two control cows and one cow suffering from bovine paraplegic syndrome (BPS). Alterations observed included a decrease of glycogen particles, changes in mitochondrial shape and electron-density, and the association of multiple elements of smooth endoplasmic reticulum with mitochondria. Peroxisomes surrounded by several layers of concentric membranes were observed. This study supports the point of view that BPS could be produced by the combined effects of different specific nutritional deficiencies.